Extrarenal manifestations of Autosomal Dominant Polycystic Kidney Disease (ADPKD)

In addition to its renal manifestations, ADPKD is a multisystemic disorder with prominent extrarenal cystic and noncystic manifestations including polycystic liver disease and cysts in diverse organ systems (pancreas, arachnoid membrane, pineal gland, and seminal vesicles), intracranial saccular aneurysms, thoracic aortic aneurysms and dissections, coronary artery aneurysms, mitral and/or tricuspid valve prolapse, aortic valve insufficiency, aortic root dilation, and possibly colonic diverticula.